The Ultimate Guide to NAD+ : Benefits, Usage, and Storage

---

Nicotinamide Adenine Dinucleotide (NAD+) is a crucial coenzyme found in every cell of the body, playing a fundamental role in cellular metabolism, energy production, and overall vitality. As we age, NAD+ levels decline, contributing to various age-related conditions, fatigue, and cognitive decline. Supplementing with NAD+ peptides may help counteract these effects and support overall wellness.

NAD+ is essential for metabolic processes, particularly in energy production through mitochondrial function. It also plays a key role in DNA repair, immune function, and neuroprotection. Studies suggest that NAD+ supplementation may support longevity, improve cognitive function, enhance muscle performance, and aid in metabolic balance.

• Cellular Energy Production: Enhances ATP production, fueling cellular activity.
• DNA Repair & Longevity: Supports SIRTUIN proteins, which regulate cellular health.
• Neuroprotection: Protects neurons from oxidative stress and improves cognitive performance.
• Anti-Aging Effects: Maintains mitochondrial function and combats age-related decline.
• Metabolic Support: Enhances insulin sensitivity and regulates metabolism.
• Immune System Boost: Aids in cellular defense mechanisms.

NAD+ levels naturally diminish over time due to increased activity of NADase enzymes, particularly CD38. Studies indicate that by age 50, NAD+ levels are nearly half of what they were in youth, leading to increased oxidative stress, reduced cellular repair, and overall metabolic decline.

• Increases energy and mental clarity
• Supports brain health and cognitive function
• Improves sleep quality and mood balance
• Aids in muscle recovery and performance
• Enhances detoxification and immune function
• Promotes healthy metabolism and fat oxidation
• Supports cardiovascular and mitochondrial health
• 
  

NAD+ peptides are typically administered through subcutaneous injections or oral supplements.

• Week 1-4: 25mg once to three times a week
• Week 5-8: 50mg once to three times a week
• Week 9+: 100mg once to three times a week

Note: Always consult with a healthcare provider before beginning any supplementation regimen.

Proper storage ensures the potency and effectiveness of NAD+ peptides:

• Dry Powder: Store at 68°F to 77°F (20°C to 25°C) away from light and moisture.
• Reconstituted Solution: Keep refrigerated at 36°F to 46°F (2°C to 8°C).
• Use By Date: Follow manufacturer guidelines for shelf life.
• 
  

To prepare NAD+ for injection:

1. 500mg Vial: Add 5mL of bacteriostatic water.
2. 1000mg Vial: Add 10mL of bacteriostatic water.
3. Refrigerate immediately after mixing.

How do I Reconstitute Video

graph TD;

    A[Obtain NAD+ Vial] --> B[Prepare Bacteriostatic Water];

    B --> C[Use Syringe to Draw Water];

    C --> D[Inject Water into NAD+ Vial];

    D --> E[Swirl Gently to Mix];

    E --> F[Refrigerate for Storage];

NAD+ peptides are commonly administered via subcutaneous injection.

1. Clean Injection Site: Use an alcohol swab.
2. Draw Up the Solution: Use a sterile syringe.
3. Pinch Skin: Choose a site at least two inches from the belly button.
4. Insert Needle: Inject at a 45 to 90-degree angle.
5. Inject the Solution: Slowly push the plunger.
6. Dispose of Needles Properly: Use a sharps container.

Drawing up a Syringe Video

Injecting Subcutaneous Tissue Video 

Most users tolerate NAD+ well, but some may experience:

• Mild headaches
• Flushing
• Gastrointestinal discomfort
• Dizziness or lightheadedness
• Temporary fatigue

If any severe reactions occur, consult a medical professional immediately.

Yes, NAD+ peptides can complement other wellness supplements, such as CoQ10, resveratrol, and vitamin B3 (niacin), which further support mitochondrial health.

Effects vary per individual, but most users report improved energy and cognitive function within 2-4 weeks.

While generally safe, individuals with pre-existing conditions, pregnant women, and those on medication should consult a healthcare provider before use.

When purchasing NAD+ peptides, it's essential to choose a reputable source that provides third-party testing and proper manufacturing standards.

NAD+ peptides offer a powerful way to support cellular health, energy production, and overall longevity. With proper storage, dosing, and administration, users can maximize the benefits of NAD+ supplementation for optimal wellness.

1. Zhang H, Ryu D, et al. "NAD+ Metabolism and Its Roles in Cellular Functions." Nature Reviews Molecular Cell Biology, 2021.
2. Rajman L, Chwalek K, Sinclair DA. "Therapeutic Potential of NAD+ Precursors in Age-Related Diseases." Cell Metabolism, 2018.
3. Grozio A, Mills KF, et al. "NAD+ Decline in Aging: Causes and Consequences." Annual Review of Nutrition, 2020.
4. Yoshino J, Baur JA, Imai SI. "NAD+ Intermediates: The Biology and Therapeutic Potential." Cell Metabolism, 2018.
5. Verdin E. "NAD+ in Aging, Metabolism, and Neurodegeneration." Science, 2015.